Short Description:
Ibuprofen
CAS Number: 15687-27-1
Molecular Formula: C13H17O2
Standard: USP32/BP2010/
Certificate: GMP
Documentation/Registration: FDA
Package: 25kg/drum
Description:
Ibuprofen
CAS Number: 15687-27-1
Molecular Formula: C13H17O2
Standard: USP32/BP2010/
Certificate: GMP
Documentation/Registration: FDA
Package: 25kg/drum
| ITEMS | LIMIT |
| CHARACTERISTICS | WHITE CRYSTALLINE POWDER |
| SOLUBILITY | PRACTICALLY INSOLUBLE IN WATER;VERY SOLUBLE IN ALCOHOL,IN METHANOL,IN ACETONE,AND IN CHLOROFORM;SLIGHTLY SOLUBLE IN ETHYL ACETATE |
| IDENTIFICATION: | A.SAMPLE UV SPECTRUM CORRESPONDS TO THAT OF THE STANDARD |
| 1. IR | |
| 2. UV | B.SAMPLE UV SPECTRUM DOES NOT DIFFER FROM THAT OF THE STANDARD BY MORE THAN 3.0% |
| 3. HPLC | C.RETENTION TIME CORRESPONDS TO THAT OF THE STANDARD |
| WATER CONTENT | NOT MORE THAN 1.0% |
| HEAVY METALS | NOT MORE THAN 0.002% |
| RESIDUAL ON LGNITION | NOT MORE THAN 0.5% |
| CHROMATOGRAPHIC PURITY | 2-[3-(2-METHYLPROPYL)PHENYL]PROPANOIC ACID:NOT MORE THAN 0.15% |
| 2-(4-METHYLPHENYL)PROPANOIC ACID:NOT MORE THAN 0.15% | |
| 2-(4-ETHYLPHENYL)PROPANOIC ACID:NOT MORE THAN 0.15% | |
| 2-(4-PROPYLPHENYL)PROPANOIC ACID:NOT MORE THAN 0.15% | |
| 2-(4-BUTYLPHENYL)PROPANOIC ACID:NOT MORE THAN 0.1% | |
| ANY UNKNOWN IMPURITY:NOT MORE THAN 0.05% | |
| TOTAL IMPURITIES:NOT MORE THAN 0.6% | |
| 4-ISOBUTYLACETOPHENONE | NOT MORE THAN 0.1% |
| ASSAY(DRY BASIS) | 97.0%-103.0% |
| ADDITIONAL TESTS | |
| RESIDUAL SOLVENTS(PETROLEUM ETHER) | NOT MORE THAN 250PPM |
| BULK DENSITY | 0.20-0.50G/ML |
| TAPPED DENSITY | 0.40-0.70G/ML |
| MEDIAN PARTICLE SIZE | 30-60UM |
